Resources
News/Events 2009
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Event5AM is proud to underwrite the scholarship program for advocates participating in the Genetic Alliance Newborn Screening Summit on December 7th and 8th in Bethesda, Maryland. Stakeholders meet to engage about a vision for the future of newborn screening. Our sponsorship enables Summit attendance by newborn screening advocates who would otherwise be unable to participate. The voice of advocates who represent the families most affected by newborn screening is critical to this process. 5AM will be in attendance; contact us at info@5amsolutions.com if you'd like to meet.Learn More/Register: Genetic Alliance Newborn Screening Summit
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Press ReleaseWeb Portal Provides Researchers and Clinicians a Forum to Further Encourage Collection and Use of Family Health History Data
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AnnouncementNCI announced the release of version 1.0 of the caIntegrator2 platform which allows researchers to create custom translational study web portals for data query and analysis. These custom portals support the integration of clinical, microarray, and medical imaging data for querying, analysis and visualization, thus enabling multidisciplinary research. This first release of caIntegrator2 supports the integration and analysis of clinical data with expression data and copy number data from caArray (Affymetrix and Agilent platforms) and with images from the National Biomedical Imaging Archive (NBIA). In addition, data can be queried and analyzed via caGrid analytic services (Comparative Marker Selection, Principal Component Analysis and GISTIC at the time of this release) or via GenePattern. Analysis results can then be either viewed at GenePattern or downloaded from the caIntegrator2 portal.
The NCI CBIIT deployment of the application can be accessed at https://caintegrator2.nci.nih.gov/caintegrator2/login.action and requires users to register for an account to access the study data that exists there. Public data from three studies are currently hosted in this portal: The Cancer Genome Atlas Glioblastoma Multiforme (TCGA GBM) study; the Director's Challenge Lung Study; and the REpository for Molecular BRAin Neoplasia DaTa (REMBRANDT), an informatics project to support the GMDI effort led by the NCI's Center for Cancer Research (CCR) Neuro-Oncology Branch. In the coming weeks, we will also make available the public data from Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Acute Lymphoblastic Leukemia (ALL) study and TCGA Ovarian study at this portal. Please contact us if you would like to host your data at the CBIIT instance as well. This work describes a method to streamline mass spectrometry analysis of proteins by using computational methods. The method uses computational prediction of peptide sequences to replace the time-consuming and expensive MS/MS step that is commonly used.Details: caIntegrator -
In the Media5AM CEO Challenges Congressman: Introduce Legislation to Support Biotech Innovation (BioWorld Today)Abstract: At a health policy forum in today's Mid-Atlantic Bio conference, Rep. Charles Boustany (R-La.) prodded biotech leaders to lobby Congress for support on biotech innovation programs such as SBIRs (Small Business Innovation Research grants). [more]Full Article: "Cash-Hungry Biotechs Clamor for Long-Awaited SBIR Re-up" (Subscription required)
Mid-Atlantic Bio Conference: http://midatlanticbio.org/
Congressman's Website: Rep. Charles Boustany (R-La.)
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In the MediaFull Article: "Family history can hint at how the future will shape up"
Learn More About FHH: 5AM Featured Project: FHH
Use the Tool: http://familyhistory.hhs.gov
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Press ReleaseWinners were chosen based on measures including generous pay and benefits, challenging and interesting work, great work-life balance, opportunities to learn and grow, financial stability, and more.
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Press Releasefor the National Cancer Institute's cancer Biomedical Informatics Grid® Compatibility Program
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Press Release$691,930 awarded for in silico center of excellence
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In the MediaAbstract: Dr. Francis S. Collins, director of the National Institutes of Health, mentions the Family Health History software in his article in Parade. "Bob, a patient I've worked with, was only 32 when he was diagnosed with colon cancer. Upon sharing the news with his family, he learned that several relatives also had colon cancer, including his great-grandmother, his grandmother, and two of his grandmother's siblings. But what did Bob's family history mean? And who else might be at risk?"Full Article: Dramatic Breakthroughs in Cancer Treatment (Parade Magazine)
Learn More About FHH: 5AM Featured Project: FHH
Use the Tool: http://familyhistory.hhs.gov
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In the MediaAbstract: The Family Health History application, which 5AM developed for the US Surgeon General, was mentioned in a Woman's Day magazine article, "What Doctors Wish You'd Do." Tracking your family health history can help your doctor understand your risk of certain diseases, and prescribe lifestyle changes and screening tests to improve your health.Full Article: What Doctors Wish You'd Do
Learn More About FHH: 5AM Featured Project: FHH
Use the Tool: http://familyhistory.hhs.gov
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AnnouncementDescription: This work describes a method to streamline mass spectrometry analysis of proteins by using computational methods. The method uses computational prediction of peptide sequences to replace the time-consuming and expensive MS/MS step that is commonly used.
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Press ReleaseSix Organizations Receive 5% of Net Income
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In the MediaAbstract: 5AM's participation in NCI's Support Service Provider program is featured in a GenomeWeb story on the topic. 5AM's CTO Todd Parnell discusses our project to deploy caBIG-compatible services to "the cloud" using the Google App Engine.
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EventAs an NCI licensed Support Service Provider, we're proud to participate in the caBIG® Annual Meeting. We're exhibiting in the World's Fair (see us at Booth 17), staffed from 5:30-7:30pm each evening. You'll also find us on the program:
- 5AM's Will FitzHugh will join the panel on Life Sciences Roadmap for Integrative Solutions, at 10:15am Tuesday morning
- 5AM Poster Presentations:
- caIntegrator2: Translational Research Tool for the 21st Century
- caGrid Services Without a Relational Data Store: Google App Engine
- FIREBIRD is the subject of a poster by NCI's Division of Cancer Prevention.
- See our client, James Matthew from ABRC, on Tuesday from 1:15-2:30pm, speak about caBIG® Supporting Biospecimen Management. He'll discuss the effort ABRC is undertaking for a statewide biorepository, for which 5AM is developing the software.
- Tuesday from 2:00-3:30pm, find 5AM on the panel of the session Introducing Licensed caBIG® Support Service Providers: Customized Technical Support
Event Details: https://cabig.nci.nih.gov/2009AnnualMeeting
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In the MediaAbstract:My Family Health Portrait, which 5AM developed for the U.S. Surgeon General is featured in the Wall Street Journal.
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In the MediaAbstract: At the JavaOne show, software architects discussed how the eHarmony has been testing out different variations of its matchmaking models using Hadoop and Elastic MapReduce on top of Amazon Web Services (AWS).
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Event5AM Solutions is proud to sponsor the Bio-IT Coalition's Scholarship Award. The scholarship funded by 5AM honored Aristide Chikando, a Doctoral Candidate. Bioinformatics and Computational Biology. College of Science. George Mason University. See photo of 5AM's Joe Croghan and Aristide.Event Details: Bio-IT Coalition's Scholarship
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In the MediaAbstract: Arizona biomedical researchers who have long found it difficult to share information about tissue samples with their collaborators will soon find their translational research burdens eased by an agreement between the Arizona Biomedical Research Commission (ABRC), a state-run research contract coordinator, and 5AM Solutions, a software developer for academic, government, commercial and non-profit life sciences organizations.
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Event5AM's Will FitzHugh Co-Authors Posters and Presentation at AACR MeetingWill FitzHugh, 5AM's Senior Director of Bioinformatics, is co-author on two posters and a presentation at this year's American Association of Cancer Research meeting in Denver, Colorado. The posters and the presentation describe work in identifying and validating serum biomarker panels for early detection and diagnosis of lung, colorectal and pancreatic cancer. The work leverages Celera's mass spectrometry-based discovery platform and uses ELISA immunoassays to directly measure concentrations of proteins in the serum from cancer patients. Mr. FitzHugh performed the statistical analysis and produced predictive models for identifying serum from patients with disease.Conference Details: 2009 AACR Annual Meeting
Poster: Mass spectrometry-based identification and validation of protein biomarkers for detection of lung cancer
Poster: Colon cancer serum protein markers identified using mass-spectrometry based discovery platform
Presentation: Pancreatic cancer serum protein markers identified using mass-spectrometry based discovery platform
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Press ReleaseOffice of the National Coordinator for Health IT session explores 5AM-developed Surgeon General's software as first step toward interoperable, standards-based electronic health tools.Conference Details: HIMSS09 - Healthcare IT Conference and Exhibition
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In the MediaAbstract: As translational medicine efforts evolve, institutions are looking to build "virtual" biorepository management systems that combine open source tools from the National Cancer Institute's Cancer Biomedical Informatics Grid with commercial software development and support.
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In the MediaAbstract: 5AM Solutions is leveraging the NCI's open source tissue software to rapidly deploy a virtual tissue bank system for the state of Arizona.Full Article: http://cabig.cancer.gov/media/links/April_09/arizona.asp
Project Page: 5AM Solutions Virtual Tissue Bank -
EventEvent Description: 5AM will discuss its role in providing life science software solutions in the Washington, DC area at the BIO IT Coalition's March 18 event, 11:30am - 1:30pm at George Mason University's Prince William County Campus, Bull Run Hall, Room 130, 10900 University Boulevard, Manassas, VA 20110. Free to BIO IT Coalition members; $25 fee otherwise.Event Info & Registration: http://www.bioitcoalition.org/events.html
BIO IT Coalition: http://www.bioitcoalition.org/ -
AnnouncementDescription: 5AM supported the Government of Mexico in its adoption and deployment of the Family Health History application, which 5AM developed for the US Department of Health and Human Services (HHS).Mexican Deployment of the Tool: http://retratodefamilia.inmegen.gob.mx:8080/fhh-web/home.action?request_locale=es
National Institute of Genomic Medicine: http://www.inmegen.gob.mx/
Inmegen News Announcement: Inmegen News
HHS Version of the Tool: https://familyhistory.hhs.gov/ -
EventEvent Description: 5AM's Steve Lustbader moonlights as a forward for the DC Invaders hockey team. 5AM is supporting the Invaders' charity hockey game at DC's Verizon Center on Friday, April 3, following the Caps/Sabres faceoff. This special event benefits "Hockey Fights Cancer." We welcome your questions, comments, or attendance at the game!
Event Flyer: Download PDF
Hockey Fights Cancer: http://www.nhl.com/ice/page.htm?id=25343
DC Invaders: http://www.dcinvaders.com/ -
In the MediaAbstract: Earlier this month, caBIG® released new upgrades to caArray. The open-source, web-accessible tool facilitates the annotation and management of array data, and enables data exchange between local installations of the tool across the caBIG® grid infrastructure, caGrid. The new version of caArray is intended to help investigators run faster, more powerful searches and provides significant enhancements.
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Press ReleaseThe State’s First Virtual Tissue Bank Will Foster Greater Collaboration and Facilitate Clinical Research
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In the MediaAbstract: Brent defended the benefits that can be unleashed through technologies like electronic health records.Original Editorial: Your E-Health Records
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AnnouncementAbstract: 5AM has joined with organizations in academe, research, government, and industry to work toward linking research and patient care.Full Article: http://www.bighealthconsortium.org/about/participants
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AnnouncementAbstract: Free new service developed by 5AM allows families to complete and understand their health histories. "Information is at the root of good health," says HHS Secretary Leavitt.
